Express Scripts Reports Full Year EPS of $3.10, Up 30%

Fourth Quarter EPS of $0.83, Up 20%


ST. LOUIS, Feb. 25, 2009 (GLOBE NEWSWIRE) -- Express Scripts, Inc. (Nasdaq:ESRX) announced fourth quarter and full year net income from continuing operations of $206.4 million and $779.6 million, or $0.83 and $3.10 per diluted share, respectively. These results include $11.3 million ($7.3 million after tax) for charges related to a previously disclosed security incident. Fourth quarter and full year EPS grew 20% and 30%, respectively, over adjusted 2007 results.

The Company reported fourth quarter cash flow from continuing operations of $368.5 million, up from $342.3 million last year. For the year, the Company reported cash flow from continuing operations of $1,095.6 million, up from $848.1 million in 2007.

"We remain intensely focused on what matters to our plan sponsors -- lowering their pharmacy spend while enabling better health and value," stated George Paz, president, chief executive officer and chairman. "Now more than ever, our aligned business model is proving critical in driving waste out of the pharmacy benefit."

"As we look to 2009 and beyond, we believe as a result of our differentiated business model, we are best positioned to deliver superior value to our clients and superior growth for our stockholders."

Fourth Quarter 2008 Review (comparative data for 2007 is reflected in tables 2-4 below)



 * The Company's industry-leading generic utilization rate increased to
   67.3% from 63.7% last year.
 * Specialty and Ancillary Services ("SAAS") operating income increased
   to $19.9 million, up 84% from $10.8 million in 2007 and increased
   32% sequentially from $15.1 million in the third quarter of 2008.
 * EBITDA increased 13% to $363.2 million from $320.8 million last year
   and EBITDA per adjusted claim increased 16% to $2.90 from $2.49 last
   year.

Full-year 2008 Review (comparative data for 2007 is reflected in tables 2-4 below)



 * Generic utilization for 2008 averaged 66.1%, up from 61.8% last
   year.
 * Operating income increased to $1,280.5 million, up 18% from $1,088.4
   million last year.
 * EBITDA increased 16% to $1,378.2 million from $1,185.9 million last
   year, and on a per adjusted claim basis, was $2.72, a 16% increase
   over 2007.
 * ROIC increased to 26.8%, up from 23.7% last year.

2009 Guidance

The Company reaffirmed its 2009 earnings per share guidance in the range of $3.63 to $3.73.

About Express Scripts

Express Scripts, Inc. is one of the largest PBM companies in North America, providing PBM services to thousands of client groups, including managed-care organizations, insurance carriers, employers, third-party administrators, public sector, workers' compensation, and union-sponsored benefit plans.

Express Scripts provides integrated PBM services, including network-pharmacy claims processing, home delivery services, benefit-design consultation, drug-utilization review, formulary management, and medical- and drug-data analysis services. The Company also distributes a full range of biopharmaceutical products directly to patients or their physicians, and provides extensive cost-management and patient-care services.

Express Scripts is headquartered in St. Louis, Missouri. More information can be found at http://www.express-scripts.com, which includes expanded investor information and resources. More information on the Center for Cost-Effective Consumerism can be found at http://www.consumerology.org.

The Express Scripts, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=5700

SAFE HARBOR STATEMENT

This press release contains forward-looking statements, including, but not limited to, statements related to the Company's plans, objectives, expectations (financial and otherwise) or intentions. Actual results may differ significantly from those projected or suggested in any forward-looking statements. Factors that may impact these forward-looking statements can be found in the Management's Discussion and Analysis of Financial Condition and Results of Operations in our Form 10-K on file with the SEC. A copy of this form can be found at the investor relations section of Express Scripts web site at http://www.express-scripts.com.

We do not undertake any obligation to release publicly any revisions to such forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.



                         EXPRESS SCRIPTS, INC.
            Unaudited Consolidated Statement of Operations

                          Three Months Ended          Year Ended
                             December 31,            December 31,
                        ----------------------  ----------------------
 (in millions, except
   per share data)         2008        2007        2008        2007
                        ----------  ----------  ----------  ----------

 Revenues (1)            $ 5,505.9   $ 5,553.4  $ 21,978.0  $ 21,824.0
 Cost of revenues (1)      4,954.1     5,091.0    19,937.1    20,065.2
                        ----------  ----------  ----------  ----------
  Gross profit               551.8       462.4     2,040.9     1,758.8
 Selling, general and
  administrative             213.3       182.9       760.4       698.0
                        ----------  ----------  ----------  ----------
 Operating income            338.5       279.5     1,280.5     1,060.8
                        ----------  ----------  ----------  ----------
 Other (expense) income:
  Non-operating charges,
   net                          --          --        (2.0)      (18.6)
  Undistributed loss
   from joint venture           --        (0.2)       (0.3)       (1.3)
  Interest income              2.3         4.1        13.0        12.2
  Interest expense           (21.6)      (29.3)      (77.6)     (108.4)
                        ----------  ----------  ----------  ----------
                             (19.3)      (25.4)      (66.9)     (116.1)
                        ----------  ----------  ----------  ----------
 Income before income
  taxes                      319.2       254.1     1,213.6       944.7
 Provision for income
  taxes                      112.8        88.0       434.0       344.2
                        ----------  ----------  ----------  ----------
 Net income from
  continuing operations      206.4       166.1       779.6       600.5
 Net income (loss) from
  discontinued
  operations, net of tax       0.4       (27.6)       (3.5)      (32.7)
                        ----------  ----------  ----------  ----------
 Net income              $   206.8   $   138.5  $    776.1  $    567.8
                        ==========  ==========  ==========  ==========

 Weighted average
  number of common
  shares outstanding
  during the period:
  Basic:                     247.6       252.3       248.9       260.4
  Diluted:                   249.9       256.0       251.8       264.0

 Basic earnings (loss)
  per share:
  Continuing operations  $    0.83   $    0.66  $     3.13  $     2.31
  Discontinued
   operations                 0.00       (0.11)      (0.01)      (0.13)
  Net earnings                0.84        0.55        3.12        2.18

 Diluted earnings (loss)
  per share:
  Continuing operations  $    0.83   $    0.65  $     3.10  $     2.27
  Discontinued
   operations                 0.00       (0.11)      (0.01)      (0.12)
  Net earnings                0.83        0.54        3.08        2.15

 (1) Includes retail pharmacy co-payments of $708.1 million and $860.5
 million for the three months ended December 31, 2008 and 2007,
 respectively, and $3,153.6 million and $3,554.5 million for the years
 ended December 31, 2008 and 2007, respectively.



                         EXPRESS SCRIPTS, INC.
                 Unaudited Consolidated Balance Sheet

                                              December 31, December 31,
 (in millions, except share data)                 2008         2007
                                                ---------    ---------
 Assets
 Current assets:
  Cash and cash equivalents                       $ 530.7      $ 434.7
  Restricted cash and investments                     4.8          2.2
  Receivables, net                                1,155.9      1,184.6
  Inventories                                       203.0        166.1
  Deferred taxes                                    118.2        121.1
  Prepaid expenses and other current assets          31.2         18.7
  Current assets of discontinued operations            --         40.4
                                                ---------    ---------
   Total current assets                           2,043.8      1,967.8
 Property and equipment, net                        222.2        215.5
 Goodwill                                         2,881.1      2,695.3
 Other intangible assets, net                       332.6        342.0
 Other assets                                        29.5         30.2
 Non-current assets of discontinued operations         --          5.6
                                                ---------    ---------
   Total assets                                 $ 5,509.2    $ 5,256.4
                                                =========    =========

 Liabilities and Stockholders' Equity
 Current liabilities:
  Claims and rebates payable                    $ 1,380.7    $ 1,258.9
  Accounts payable                                  496.4        517.3
  Accrued expenses                                  420.5        432.5
  Current maturities of long-term debt              420.0        260.1
  Current liabilities of discontinued operations      4.1          6.2
                                                ---------    ---------
   Total current liabilities                      2,721.7      2,475.0
 Long-term debt                                   1,340.3      1,760.3
 Other liabilities                                  369.0        324.7
                                                ---------    ---------
   Total liabilities                              4,431.0      4,560.0
                                                ---------    ---------

 Stockholders' equity:
  Preferred stock, 5,000,000 shares authorized,
   $0.01 par value per share;and no shares
   issued and outstanding                              --           --
  Common stock, 1,000,000,000 shares authorized,
   $0.01 par value; shares issued: 318,958,000
   and 318,886,000, respectively; shares
   outstanding: 247,649,000 and 252,371,000,
   respectively                                       3.2          3.2
  Additional paid-in capital                        640.8        564.5
  Accumulated other comprehensive income              6.2         20.9
  Retained earnings                               3,361.0      2,584.9
                                                ---------    ---------
                                                  4,011.2      3,173.5
 Common stock in treasury at cost, 71,309,000
  and 66,515,000 shares, respectively            (2,933.0)    (2,477.1)
                                                ---------    ---------
   Total stockholders' equity                     1,078.2        696.4
                                                ---------    ---------
   Total liabilities and stockholders' equity   $ 5,509.2    $ 5,256.4
                                                =========    =========



                         EXPRESS SCRIPTS, INC.
       Unaudited Condensed Consolidated Statement of Cash Flows

                                                         Year Ended
                                                        December 31,
                                                     -----------------
 (in millions)                                         2008      2007
                                                     -------   -------

 Cash flows from operating activities:
 Net income                                          $ 776.1   $ 567.8
 Net loss from discontinued operations, net of tax       3.5      32.7
                                                     -------   -------
  Net income from continuing operations               779.6      600.5
 Adjustments to reconcile net income to net cash
  provided by operating activities:
  Depreciation and amortization                         97.7      97.5
  Deferred income taxes                                 33.8       4.1
  Bad debt expense                                      30.1      36.7
  Employee stock-based compensation expense             40.2      31.6
  Other, net                                            20.7       0.5
 
 Changes in operating assets and liabilities, net
  of changes resulting from acquisitions:
  Receivables                                           21.9      71.6
  Inventories                                          (38.0)     25.3
  Other current and non-current assets                   5.4       6.9
  Claims and rebates payable                           113.0     (16.8)
  Other current and non-current liabilities             (8.8)     (9.8)
                                                     -------   -------
 Net cash provided by operating activities --
  continuing operations                              1,095.6     848.1

 Net cash provided by (used in) operating activities
  -- discontinued operations                             7.4     (20.8)
                                                     -------   -------
 Net cash flows provided by operating activities     1,103.0     827.3
                                                     -------   -------
 Cash flows from investing activities:
  Purchases of property and equipment                  (85.8)    (75.0)
  Acquisition, net of cash acquired, and investment
   in joint venture                                   (251.5)    (14.3)
  Sale of marketable securities                           --      34.2
  Short term investment transferred from cash          (49.3)       --
  Cash received from short term investment              38.9        --
  Proceeds from sale of businesses                      27.7        --
  Other                                                 (0.6)     (0.7)
                                                     -------   -------
 Net cash used in investing activities -- continuing
  operations                                          (320.6)    (55.8)
 Net cash used in investing activities --
  discontinued operations                                 --      (2.5)
                                                     -------   -------
 Net cash used in investing activities                (320.6)    (58.3)
                                                     -------   -------
 Cash flows from financing activities:
  Proceeds from long-term debt                            --     800.0
  Repayment of long-term debt                         (260.0)   (180.1)
  Repayments of revolving credit line, net                --     (50.0)
  Tax benefit relating to employee stock-based
   compensation                                         42.1      49.4
  Treasury stock acquired                             (494.4) (1,140.3)
  Deferred financing fees                                 --      (1.5)
  Net proceeds from employee stock plans                31.9      52.8
                                                     -------   -------
 Net cash used in financing activities                (680.4)   (469.7)
                                                     -------   -------

 Effect of foreign currency translation adjustment      (6.0)      4.4
                                                     -------   -------

 Net increase in cash and cash equivalents              96.0     303.7
 Cash and cash equivalents at beginning of year        434.7     131.0
                                                     -------   -------
 Cash and cash equivalents at end of year            $ 530.7   $ 434.7
                                                     =======   =======




                                Table 1
                    Unaudited Operating Statistics
                 (in millions, except per claim data)
 ---------------------------------------------------------------------
                 3 Months   3 Months   3 Months   3 Months   3 Months
                   Ended      Ended      Ended      Ended      Ended
                12/31/2008  9/30/2008  6/30/2008  3/31/2008  12/31/2007
                ------------------------------------------------------
 Revenues
 PBM               4,573.1    4,492.8    4,590.7    4,558.5    4,622.9
 SAAS                932.8      957.7      940.1     932.3       930.5
                 -----------------------------------------------------
  Total
   consolidated
   revenues        5,505.9    5,450.5    5,530.8    5,490.8    5,553.4
                 =====================================================

 Claims Detail
 Network (1)          93.8       91.5       96.1       98.2       96.9
 Home Delivery        10.1       10.3       10.3       10.1       10.3
                 -----------------------------------------------------
  Total PBM
   claims            103.9      101.8      106.4      108.3      107.2
  Adjusted PBM
   claims (2)        124.2      122.4      126.9      128.5      127.8
                 =====================================================
 SAAS claims (3)       1.0        1.1        1.1        1.1        1.2
                 -----------------------------------------------------
  Total adjusted
   claims (4)        125.2      123.5      128.0      129.6      129.0
                 =====================================================

 Per Adjusted
  Claim
 Adjusted EBITDA
  (5)            $    2.90  $    2.87  $    2.67  $    2.46  $    2.49
 ---------------------------------------------------------------------


                                 Table 2
  Calculation of Adjusted Operating Income from Continuing Operations
                             (in millions)
 ---------------------------------------------------------------------
 Quarterly Results:                       3 Months Ended 12/31/2007
                                          PBM       SAAS  Consolidated
                                       -------------------------------
 Operating income, as reported         $   280.8  $    (1.3) $   279.5
 Non-recurring legal expenses                6.0         --        6.0
 Non-recurring inventory charges in
  specialty distribution line of
  business                                    --        9.1        9.1
 Non-recurring bad debt charges in
  specialty distribution line of
  business                                    --        3.0        3.0
                                       -------------------------------
 Adjusted operating income             $   286.8  $    10.8  $   297.6
                                       ===============================

                                       -------------------------------
 Year-to-Date Results:                       Year Ended 12/31/2007
                                         PBM        SAAS  Consolidated
                                       -------------------------------
 Operating income, as reported         $ 1,037.5  $    23.3  $ 1,060.8
 Non-recurring legal expenses                6.0         --        6.0
 Non-recurring inventory charges in
  specialty distribution line of
  business                                    --        9.1        9.1
 Settlement of contractual item with
  supply chain vendor                       (9.0)        --       (9.0)
 Non-recurring bad debt charges in
  specialty distribution line of
  business                                    --       21.5       21.5
                                       -------------------------------
 Adjusted operating income             $ 1,034.5  $    53.9  $ 1,088.4
                                       ===============================

 The Company is providing adjusted operating income excluding the
 impact of non-recurring charges in order to compare the underlying
 financial performance to prior periods.
 ---------------------------------------------------------------------


                                Table 3
 Calculation of Consolidated Adjusted EBITDA from Continuing Operations
                             (in millions)
 ----------------------------------------------------------------------
                                             3 Months Ended  Year Ended
 EBITDA (5)                                    12/31/2007    12/31/2007
                                             --------------------------
  EBITDA from continuing operations, as reported $   302.7   $ 1,158.3
  Non-recurring legal expenses                         6.0         6.0
  Non-recurring inventory charges in specialty
   distribution line of business                       9.1         9.1
  Settlement of contractual item with supply
   chain vendor                                         --        (9.0)
  Non-recurring bad debt charges in specialty
   distribution line of business                       3.0        21.5
                                                 ---------------------
  EBITDA from continuing operations, adjusted    $   320.8   $ 1,185.9
                                                 =====================

 The Company is providing adjusted EBITDA excluding the impact of
 non-recurring charges in order to compare the underlying financial
 performance to prior periods.
 ---------------------------------------------------------------------




                                 Table 4
            Unaudited Earnings Excluding Non-recurring Items
                  (in millions, except per share data)
 ---------------------------------------------------------------------
                                          3 Months Ended   Year Ended
                                            12/31/2007     12/31/2007
                                          ----------------------------
 Reported income from continuing operations
  before taxes                              $      254.1  $      944.7

 Non-recurring legal expenses                        6.0           6.0
 Non-recurring inventory charges in
  specialty distribution line of business            9.1           9.1
 Settlement of contractual item with supply
  chain vendor                                        --          (9.0)
 Non-recurring bad debt charges in
  specialty distribution line of business            3.0          21.5
 Caremark transaction costs, net                      --          18.6
                                            --------------------------
 Income before tax excluding non-recurring
  items                                            272.2         990.9

 Provision for income taxes                         94.3         361.0
                                            --------------------------

 Adjusted net income from continuing
  operations                                $      177.9  $      629.9
                                            ==========================

 Weighted average number of shares
  outstanding during the period - diluted          256.0         264.0
                                            ==========================

 Diluted earnings per share excluding
  non-recurring items                       $       0.69  $       2.38

 Diluted earnings per share from continuing
  operations as reported                            0.65          2.27

 Impact of non-recurring items              $       0.04  $       0.11

                                            --------------------------
 The Company is providing diluted earnings per share excluding the
 impact of non-recurring charges in order to compare the underlying
 financial performance to prior periods.
 ---------------------------------------------------------------------

                                Table 5
                  Return on Invested Capital ("ROIC")
                             (in millions)
 ---------------------------------------------------------------------
                                                2008          2007
 Adjusted operating income                  $    1,280.5  $    1,088.4
 Income tax                                        457.9         396.6
                                            --------------------------
 Net operating profit after tax ("NOPLAT")  $      822.6  $      691.8

 Stockholders' equity                       $    1,078.2  $      696.4
 Interest bearing liabilities                    1,760.3       2,020.4
 Long-term deferred income taxes, net              313.8         278.6
                                            --------------------------
 Invested capital                           $    3,152.3  $    2,995.4

 Average invested capital                   $    3,073.9  $    2,914.0

 ROIC                                              26.8%         23.7%
 ---------------------------------------------------------------------



                        EXPRESS SCRIPTS, INC.

               Notes to Unaudited Operating Statistics
                            (in millions)

 (1) Network claims exclude drug formulary only claims where we only
     administer the clients formulary and approximately 0.5 million
     manual claims per quarter.

 (2) PBM adjusted claims represent network claims plus mail claims,
     which are multiplied by 3, as mail claims are typically 90 day
     claims and network claims are generally 30 day claims.  Adjusted
     claims calculated from the table may differ due to rounding.

 (3) Specialty and Ancillary Services (SAAS) claims represent the
     distribution of pharmaceuticals through Patient Assistance
     Programs and the distribution of pharmaceuticals where we have
     been selected by the pharmaceutical manufacturer as part of a
     limited distribution network. They also represent the
     distribution of specialty drugs through our CuraScript subsidiary.

 (4) Total adjusted claims includes PBM adjusted claims plus SAAS
     claims.

 (5) The following is a reconciliation of EBITDA from continuing
     operations to net income from continuing operations and to net
     cash provided by operating activities from continuing operations
     as the Company believes they are the most directly comparable
     measures calculated under Generally Accepted Accounting
     Principles:

                                  3 Months Ended        Year Ended
                                   December 31,        December 31,
                                ------------------  ------------------
                                  2008      2007      2008      2007
                                --------  --------  --------  --------
 Net income from continuing
  operations                    $  206.4  $  166.1  $  779.6  $  600.5
  Income taxes                     112.8      88.0     434.0     344.2
  Depreciation and amortization*    24.7      23.2      97.7      97.5
  Interest expense, net             19.3      25.2      64.6      96.2
  Undistributed loss from joint
   venture                            --       0.2       0.3       1.3
  Non-operating charges, net          --        --       2.0      18.6
                                --------  --------  --------  --------
 EBITDA from continuing
  operations                       363.2     302.7   1,378.2   1,158.3
  Current income taxes            (110.9)    (77.2)   (400.2)   (340.1)
  Interest expense less
   amortization                    (18.7)    (24.6)    (62.2)    (94.0)
  Undistributed loss from joint
   venture                            --      (0.2)     (0.3)     (1.3)
  Non-operating charges, net          --        --      (2.0)    (18.6)
  Other adjustments to reconcile
   net income to net cash
   provided by operating
   activities                      134.9     141.6     182.1     143.8
                                --------  --------  --------  --------
  Net cash provided by
   operating activities from
   continuing operations        $  368.5  $  342.3  $1,095.6  $  848.1
                                ========  ========  ========  ========

 EBITDA is earnings before other income (expense), interest, taxes,
 depreciation and amortization, or operating income plus depreciation
 and amortization. EBITDA is presented because it is a widely accepted
 indicator of a company's ability to service indebtedness and is
 frequently used to evaluate a company's performance. EBITDA, however,
 should not be considered as an alternative to net income, as a
 measure of operating performance, as an alternative to cash flow, as
 a measure of liquidity or as a substitute for any other measure
 computed in accordance with accounting principles generally accepted
 in the United States. In addition, our definition and calculation of
 EBITDA may not be comparable to that used by other companies.

 * Includes depreciation and
   amortization expense of:
     Gross profit                    6.3       6.9      26.3      31.3
     Selling, general and
      administrative                18.4      16.3      71.4      66.2
                                --------  --------  --------  --------
                                    24.7      23.2      97.7      97.5
                                ========  ========  ========  ========

            

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