Notification according to Chapter 2, Section 10 of the Finnish Securities Market Act



BIOTIE THERAPIES CORP.   STOCK EXCHANGE RELEASE 8 DECEMBER 2009 at
9.40 a.m.


Notification according to Chapter 2, Section 10 of the Finnish
Securities Market Act

Invesco Limited has through Invesco Fund Managers Limited subscribed
the 14,432,000 shares offered in the directed share issue of Biotie
Therapies Corp. (the "Company" or "Biotie"). Invesco's ownership in
the Company will exceed 1/20 (i.e. 5 %) of the total number of shares
and votes in the Company upon the new shares becoming registered on
or about 14 December 2009. Details of the share issue have been
disclosed by the Company through stock exchange releases on 4
December 2009 and 7 December 2009.

The change in holdings in accordance with Chapter 2, Section 9 of the
Finnish Securities Markets Act is described below.



+----------------------------------------------------------------------+
|Name of the      |Shares    |Holdings  |Holdings  |Holdings |Holdings |
|shareholder      |          |of shares |of shares |of votes |of votes |
|                 |          |before    |after     |before   |after    |
|                 |          |issue     |issue     |issue    |issue    |
|-----------------+----------+----------+----------+---------+---------|
|Invesco Limited  |14,432,000|0 %       |9.09 %    |0 %      |9.12 %   |
+----------------------------------------------------------------------+


The registered number of shares in Biotie is 144,320,560 and the
number of voting rights attached to the shares amounts to
143,857,305. After the new shares issued in the share issue shall be
registered with the Trade Register on or about 14 December 2009, the
number of shares in the Company shall be 158,752,560 and the number
of votes 158,289,305.

In Turku, 8 December 2009

Biotie Therapies Corp.
Timo Veromaa, President and CEO

For further information, please contact:
Virve Nurmi, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

www.biotie.com

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