Cancer Genetics to Report Biomarker Findings in Metastatic Clear Cell Renal Carcinoma Using a CGI-Designed NGS Panel at the 14th International Kidney Cancer Symposium in Miami, FL


RUTHERFORD, N.J., Nov. 07, 2015 (GLOBE NEWSWIRE) -- Cancer Genetics, Inc. (Nasdaq:CGIX) (“CGI” or “The Company”), an emerging leader in DNA-based cancer diagnostics, announced the presentation of results from a University of Utah (Huntsman Cancer Institute)-led research study at the 14th International Kidney Cancer Symposium in Miami, Florida, on November 7th, 2015. The study entitled, “Molecular Predictors of Response and Survival Outcomes in Patients With Metastatic Clear Cell Renal Cell Carcinoma (mccRCC) Treated With Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitors (VEGFTKIs)” was conducted as a collaboration between Dr. Neeraj Agarwal and CGI. The aim of the study was to investigate molecular markers predictive of response to targeted therapy, to allow better patient selection and guide towards more customized and effective therapy.

The HCI and Cancer Genetics teams worked jointly to identify molecular abnormalities or markers in the tumor samples of 89 mccRCC patients treated with targeted therapy. The specimens were subjected to DNA sequencing using a NGS panel designed by CGI specifically for renal cancer and to whole genome array-comparative genomic hybridization. After independent validation, the results of the study will aid in better selection of patients for given treatments, thus minimizing toxicities, managing costs, and facilitating individualized therapy. 

Details for the presentation are the following:

Event Name:    14th International Kidney Cancer Symposium in Miami, FL
      
Date and Time:    November 7th, 2015, 2.45PM ET
      
Study Title:    Molecular Predictors of Response and Survival Outcomes in Patients With Metastatic Clear Cell Renal Cell Carcinoma (mccRCC) Treated With Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitors (VEGFTKIs).
      

About Cancer Genetics

Cancer Genetics Inc. is an emerging leader in DNA-based cancer diagnostics. Our tests target difficult to diagnose   hematological, urogenital and HPV-associated cancers.  They are designed to guide the prognosis and treatment of these cancers with the goal of improving outcomes for patients. We have established strong clinical research collaborations with major cancer centers such as Memorial Sloan Kettering, The Cleveland Clinic, Mayo Clinic and the National Cancer Institute.

We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals and biopharmaceutical companies. Our state-of-the-art reference labs are CLIA certified and CAP accredited in the US and have licensure from several states including New York State.

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